Abstract:

Berberine, an isoquinoline alkaloid, is reported to possess excellent antibacterial properties. Berberine is found in the roots of Coptis chinensis and the stems of phellodendron. In the current study, the efficacy of berberine chloride as a new antibacterial agent on textile substrates against Staphylococcus aureus and Enterococcus faecalis was investigated. In particular, the relationship between bacterial inhibition and the concentration of berberine chloride needed to exhibit effective bacterial action was studied. Results showed berberine chloride to be an effective antibacterial agent at a minimum inhibitory concentration of 0.2% in the solution. On textile substrates such as 100% polyester, 100% nylon and 50% cotton-50% polyester blend, there was a 62-76% reduction in bacterial counts. The effectiveness of antibacterial action was retained after laundering and exposure to light.